http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102268639-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47cf73eda164a69ffa37f1808b3b518e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c506e727c8243d43775ed6817d0af521 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C23C14-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C23C14-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C23C14-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-10 |
filingDate | 2011-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50d2c3079bce2fefd8134f366bae0f91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8398ea8790b47a6fba4c8378e749119 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9813b2f7b27f472d1be4b3a80cfbfcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09b8e77b6c96a12a1ef455ffa6bbb5c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3701bd5f5f79d7ae0608cd103ae006b6 |
publicationDate | 2013-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102268639-B |
titleOfInvention | Method for preparing heparinized interface material with high biological functionality |
abstract | The invention discloses a method for preparing a heparinized interface material with high biological functionality. The method comprises the following steps of: depositing a layer of allyl amine plasma polymerization film on the surface of a substrate material subjected to sputter cleaning by adopting a pulse plasma polymerization method, and soaking the biological material deposited with the plasma polymerization film in a phosphate buffer solution (PBS) with the pH value of 2-7 for 1 to 24 hours, so that the amino on the surface is subjected to protonation; and adding heparin sodium into the PBS to ensure that the concentration is 1-10mg/ml, reacting at room temperature of 25DEG C for 1 to 24 hours, fully rinsing by using distilled water, and drying to obtain the target material. In the method, a heparin monomolecular layer is constructed on the surface of the plasma polymerization film by a soaking self-assembly mode only; and the preparation process is easy and convenient to operate, expensive special equipment is not needed and the preparation cost is low. |
priorityDate | 2011-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.