http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102264716-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
filingDate | 2009-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102264716-B |
titleOfInvention | For preventing and treat the substituted benzofuran of bone related disease chromene and related compound |
abstract | The benzofuran that the present invention relates to there is the new substituted of formula I chromene and related compound, its salt and chirality, not chiral derivatives;Wherein, R 1 、R 2 、R 3 、R 4 、R 5 、R 6 、R 7 、R 8 Under independently selected from: hydrogen, optionally substituted alkyl, optionally substituted thiazolinyl, optionally substituted alkoxyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted alkylthio group, optionally substituted amino, optionally substituted acyl amino, optionally substituted virtue amino, optionally substituted acyl sulfenyl, optionally substituted acyl group, optionally substituted aroyl, optionally substituted acyloxy, optionally substituted thio acylamino, halogen, nitrile, esters, hydroxyl, sulfydryl, borontrifluoride carbon, nitro, but it is not limited to this;Wherein, R 1 R 2 Or R 2 R 3 Or R 6 R 7 Can connect and be formed five-membered ring or hexatomic ring, such as optionally substituted furan, optionally substituted dihydrofuran, optionally substituted pyrans;Maybe can be connected by methylene dioxy part;Wherein, the following unit constituted of X choosing: optional ketone group, optional methylene, optionally substituted methylene, optionally substituted alkene;Wherein, Y and Z is selected from lower unit: CH, C OH, C Me, C OMe, additional conditions be the key between Y and Z be singly-bound;Wherein, Y and Z can be carbon atom, additional conditions be the key between Y and Z be double bond.General formula compound is used for preventing and treating bone related disease. |
priorityDate | 2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 438.