http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102260297-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706 |
filingDate | 2011-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a073107591080df9160557c5396a3f1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad147d4a95a9cd32b7e4870fa7d11103 |
publicationDate | 2013-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102260297-B |
titleOfInvention | Trehalose amide derivative as well as preparation method thereof and application thereof |
abstract | The invention relates to a trehalose amide derivative as well as a preparation method thereof and an application thereof, wherein 6,6'-di(2-hydroxy benzamido)-6,6'-didesoxy-alpha, alpha-D-trehalose shows more superior activity against invasion of colon cancer 26-L5 cells than a natural product Brartemicin; IC50 is 0.20 micrograms per milliliter (0.33 microns); and the 6,6'-di(2-hydroxy benzamido)-6,6'-didesoxy-alpha, alpha-D-trehalose shows no cytotoxicity while the IC 50 is 10 micrograms per milliliter, shows antitumor invasion activity with high selectivity and is used for preparing drugs for preventing and treating invasion and transfer of colon cancers and the like. |
priorityDate | 2011-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.