http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102250127-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6077d9bd8b6ee0093203fdc84b99bd6c |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 |
filingDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bbb99de4fd0cfedf53cbf0bc73b8f82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdfbca2316372b1eca3512e862337e1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5a2fd8017dd59db80a1e8a46fe20b3a |
publicationDate | 2011-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102250127-A |
titleOfInvention | Tetrahydrocarboline derivatives modified by two amino acids and their preparation methods and applications |
abstract | The invention discloses two amino acid modified tetrahydrocarboline derivatives, a preparation method and application thereof. In the present invention, a series of (1R,3S)-1-[ 1-(1R, 3S)-tetrahydro β-carboline-3-formyl amino acid-1-yl-methyl]-tetrahydro β-carboline-3-formyl amino acid derivatives and their intermediates, and to These derivatives were evaluated for in vitro antiplatelet aggregation activity and in vivo antithrombotic activity. The method of the invention is simple, the raw materials used are easy to obtain, safe and cheap, and the obtained product has anti-platelet aggregation activity and antithrombotic activity, which indicates that (1R, 3S)-1-[1-(1R, 3S)-tetrahydroβ-carba The clinical application prospect of pheno-3-carboline-3-formyl amino acid as an antithrombotic agent. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103159758-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103450067-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103450067-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103159758-B |
priorityDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.