| abstract |
The invention relates to a new class of (thio) barbituric acid compounds and applications thereof, belonging to the field of chemical medicine. Specifically, it relates to compounds as shown in formula I and uses thereof, wherein, R 1 is hydrogen or methyl; R 2 is a benzene ring containing different substituents, a pyridine ring containing different substituents, cyclohexyl, pyrimidinyl , benzyl or naphthalene ring group; R 3 , R 4 , R 5 , R 6 and R 7 are hydrogen or methyl; X is oxygen or sulfur atom. Tests show that the compound represented by the formula I has a good effect on treating metabolic diseases such as diabetes and obesity, and provides a new option for preparing drugs for metabolic diseases. |