http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102247326-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_078cb8366425c7f7bb46338421d23406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3646626b06a1d7de707b2594f5cfa6f1 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 |
| filingDate | 2010-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd9d9ab647ecfd4adb01812b6312985f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d302552872e205d7a3e2b9f125fbec4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6d50d91204b593bab07be2b1a1c5c9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_534d87c901692c838e516dbc968bb1c6 |
| publicationDate | 2013-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102247326-B |
| titleOfInvention | Oral chronopharmacologic drug delivery mini-pill preparation of propranolol and its salts |
| abstract | The invention discloses an oral chronopharmacologic drug delivery mini-pill preparation of propranolol and its salts. The preparation comprises a quick release pill core containing 40-120mg of propranolol and its salts, a slow release layer, an alkaline layer, and a retardation layer, or comprises a slow release pill core containing 40-120mg of propranolol and its salts, the alkaline layer, and the retardation layer, wherein the retardation layer which contains polyacrylic resin III has a weight of 80-200% of the pill core, and the alkaline layer which is a medicinal water-soluble alkaline accessory has a weight of 10-30% of the pill core. The preparation has a characteristic that a medicament which is not immediately released after being orally taken is slowly released from the mini-pill when going through a time lag for 3-4h, and the slow release time can achieve 12-16h, so the daytime blood pressure can be stably controlled, and a purpose that the blood pressure in ten hours or so of early-morning wakefulness and daytime are stably controlled can be achieved. |
| priorityDate | 2010-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.