http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102247316-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9de52bba13e16028dffa8775e3f3f28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 2011-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91d5b4c7702133105297862839b5d916 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53bc13966aecf691c0ff169800095b1f |
| publicationDate | 2013-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102247316-B |
| titleOfInvention | Hydrophobic coating for controlling drug release and preparation method thereof |
| abstract | The invention relates to a hydrophobic coating for controlling drug release and a preparation method thereof, belonging to the field of chemical materials and biological medicine. The hydrophobic coating comprises a drug layer and a combined layer which is formed by hydrophobic coatings variable with time, wherein the hydrophobic coatings variable with time are covered over the drug layer and have a structure of particles, beads or fibers, the size of particles in the particle structure is 50 nm to 5 mu m, the diameter of a single bead and fiber in the bead structure are 100 nm to 5 mu m and 50 nm to 2 mu m respectively, and the diameter of fiber in the fiber structure is 100 nm to 5 mu m. The preparation method is to fix a substrate with the drug layer, to control the concentration of each high molecular solution and to obtain the hydrophobic coating through the method of electrostatic spraying. When the hydrophobic coating variable with time provided in the invention is immersed in an aqueous solution, surface hydrophobicity of the coating changes with the increases of time, and therefore the rate that water molecules enter into and go out of the coating is regulated, thereby realizing further regulation of the drug release rate of a sustained release agent as a whole and satisfying clinical treatment requirements for surface dosing with medical instruments. |
| priorityDate | 2011-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.