http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102241735-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54244b4358a1cca44e2f53e248cf5f66 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f11cc888fe438202c623e308ad13211c |
| publicationDate | 2014-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102241735-B |
| titleOfInvention | Polypeptide used for prevention and treatment of acute coronary syndrome and anticoagulation antithrombotic therapy and application thereof |
| abstract | The invention relates to a polypeptide used for prevention and treatment of acute coronary syndrome and anticoagulation antithrombotic therapy and application thereof. A sequence of the polypeptide disclosed by the invention is P1 Pro-Ser-Hyp-Gly-Asp-TrpP2 Pro-Ser-Hyp-Gly-Asp-Trp-ArgP3 Pro-Ser-Lys-Gly-Asp-TrpP4 Pro-Ser-Val-Gly-Asp-TrpP5 Pro-Ser-Nva-Gly-Asp-Trp-ArgP6 Pro-Ser-Pro-Gly-Asp-TrpP7 Pro-Ser-Thz-Gly-Asp-Trp, the polypeptide is independently used or combined with aspirin, clopidogrel or heparin, is used for inhibiting platelet aggregation and thrombosis and is taken as an effective ingredient for preparing a medicine used for prevention and treatment of acute coronary syndrome, unstable angina and acute myocardial infarction and intervention therapy of anticoagulation antithrombotic therapy. The polypeptide provided by the invention can be combined with a human blood platelet GPIIb-IIIa receptor, and has the capabilities of blocking blood platelet aggregation induced by adenosine diphosphate, arachidonic acid and thrombin and effectively inhibiting coronary thrombosis and femoral thrombosis. |
| priorityDate | 2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 122.