http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102229635-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8be6a6c990669567cc455d32b00535e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
| filingDate | 2005-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7a2b88f45b2e760ae32ceac09e1b016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ea33444a64d34375712251840074777 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1640850c5aebeb33b3e378bfdba43011 |
| publicationDate | 2015-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102229635-B |
| titleOfInvention | Process for the preparation of estrone and/or estradiol derivatives |
| abstract | The present invention relates to a process for the preparation of estrone and/or estradiol derivatives. The present invention also relates to a process for the preparation of compounds of general formula II , wherein R and R are independently hydrogen or hydroxyl or hydrocarbyl; or wherein R and R together are oxygen connected by a double bond; R is hydrogen; R' 4 is a nitrobenzophenone group, and R 5 and R 6 are independently hydrogen or hydroxyl or a hydrocarbon group; the method starts from a compound of general formula I, wherein R 1 , R 2 , R 3 , R 5 and R 6 The definition is as above, and R 4 is hydrogen; wherein the compound of general formula I is reacted with 2-chloro-5-nitrobenzophenone under basic conditions in the presence of alkanol solvent, and the compound of general formula II is reacted Crystallized directly from the alkanol solvent. Complexes of alkanols and compounds of general formula II obtained from the above-mentioned methods, and methods of using the above-mentioned methods or complexes. |
| priorityDate | 2004-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID468119147 |
Total number of triples: 18.