http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102229588-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b93c2aafeb1bcb1019daee345cc8f141 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2011-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98d263efba0a6e4de66a18418517e599 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ce2d48755a5dde586d95ac21ca2e71c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3afeeaf2d68a090dadc3758a8e1d55a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3c31405cee5cb36c867a5d5ef6c7a87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37bd12136360cd75bde96b6319e1add0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b414afaf5a0c76877785b617930dacc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a89bd68fdca87622497259f802d93d4 |
| publicationDate | 2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102229588-B |
| titleOfInvention | Briarane type diterpenoid compounds with anti-tumor and antibacterial activities and application thereof |
| abstract | The invention relates to the technical field of medicines, discloses 53 novel Briarane type diterpenoid compounds with anti-tumor and antibacterial activities, i.e. gemmacolides G-Z and gemmacolides ZI-ZXXXIII, which are obtained through the separation of marine animal gorgonian Dichotella gemmacea, and also discloses two known compounds, i.e., Juncin O and Junceellolide C. Experiments of anti-tumor and antibacterial activities in vitro show that the compounds disclosed by the invention have obvious inhibiting effects on multiple tumor cells such as A549 (human lung cancer cells), U251 ( human brain glioma cells) and MG63 (human bone sarcoma cells) and the like and has obvious bacteriostatic activity on anther smut fungus, septoria musiva septoria tritici, escherichia coli and enormous bacillus and the like; and therefore, the compounds can be used for preparing anti-tumor or antibacterial medicines. The invention has the advantages of providing a leading compound for the research of new anti-tumor or antibacterial medicines and being beneficial to the development and utilization of ocean medicinal resources. |
| priorityDate | 2011-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.