http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102229561-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ee33b0e3e7398cf6fc957eeee59d510 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-48 |
filingDate | 2011-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c404afccaa2e6371c6c4a93f9e9667f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a50e0ae1011286ea50c7fe68356cca35 |
publicationDate | 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102229561-B |
titleOfInvention | Method for preparing 2, 2-disubstituted 1, 2-dihydro quinoline derivative |
abstract | The invention discloses a method for preparing a 2, 2-disubstituted 1, 2-dihydro quinoline derivative. The method comprises the following steps of: carrying out cyclization reaction on substituted aniline, propargyl alcohol and a catalyst in a solvent in an inert atmosphere, and obtaining the 2, 2-disubstituted 1, 2-dihydro quinoline derivative as shown in a structural general formula I in the specification after the reaction is ended. In the method, a cuprous compound/cupric compound binary system is used as the catalyst. The substituted aniline is aniline with one or multiple substituent groups on benzene rings; and the propargyl alcohol is 1, 1-alkyl substituted propargyl alcohol. The method has the advantages that the cheap, safe and easily available catalyst is adopted, the reaction conditions are simple, convenient and environment-friendly, meanwhile, the catalyst system shows up high efficiency and selectivity; and the method has an important application value. |
priorityDate | 2011-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID466326222 |
Total number of triples: 16.