http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102228449-A

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filingDate 2011-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84ecc59d9582962023d6663baf4d2c91
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publicationDate 2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102228449-A
titleOfInvention Gastrodin chronopharmaceutical medicine delivery preparation
abstract The invention discloses a gastrodin chronopharmaceutical medicine delivery preparation. The preparation consists of a coating and a tablet core containing gastrodin, an inner layer of the coating is an isolated layer, and an outer layer of the coating is a controlled release layer, wherein the isolated layer is made of hydroxypropyl methylcellulose, and the weight of the isolated layer accounts for 10 to 20 percent of the weight of the tablet core; and the controlled release layer is made of film coating agent and plasticizer, the weight ratio of the film coating agent to the plasticizer is 1:(0.1-0.3), and the weight of the controlled release layer accounts for 5 to 15 percent of the weight of the tablet core. The gastrodin is easily soluble in water, so the preset time lag is achieved by increasing the weight of the isolated layer and the controlled release layer of the coating, so that the aim that the gastrodin is released after being taken for 4 to 6h is fulfilled. The preparation is applicable to insomniacs who suffer from insufficient sleep caused by early morning awakening, is easy to prepare, and can be industrially produced conveniently.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105395907-B
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priorityDate 2011-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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