http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102219670-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b93c2aafeb1bcb1019daee345cc8f141 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 |
filingDate | 2011-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68dbbc766e994a018f30ea796227a187 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec80624e72537a83e29fcde283e19383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a844fd87d7ee9b417e35f0fceb06404e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ed23568be02a6a895043bc31fcc4326 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bade02285a4bae08cf533463397a4f2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dc876d23712e5138d3faf3300ee7b7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a79bc542b47245b86501807d42835726 |
publicationDate | 2013-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102219670-B |
titleOfInvention | Linear chain polyketone compounds and application thereof |
abstract | The invention relates to the technical field of medicines, in particular to linear chain polyketone compounds separated from marine poriferans and application thereof in preparation of medicines for treating tumors, diabetes and obesity or inhibitors for protein tyrosine phosphatase-1B(PTP1B). The in vitro anti-tumor tests and the PTP1B inhibition tests show that the compound C17H32O4 has obvious inhibiting activity on human colon cancer cells HCT-116 and PTP1B, so that the compound can be used for preparing anti-tumor medicines or PTP1B inhibitors and medicines for treating diabetes, obesity and complications caused by diabetes and obesity. The invention provides novel lead compounds for developing new anti-tumor medicines or medicines for treating diabetes and obesity, and has great significance for the development and the utilization of Chinese marine medical biological resources. |
priorityDate | 2011-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.