| abstract |
The present invention relates to a novel process for the preparation of 9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalene-5-amine comprising a) ring Pentadiene with CXCl 3 , where X is chlorine or bromine, reacts to compounds of formula II in the presence of a free radical initiator, or aa) cyclopentadiene with CXCl 3 , where X is chlorine, in the presence of a metal catalyst , the reaction is a compound of formula II, wherein X is chlorine, b) the compound of formula II is reacted with a base in the presence of a suitable solvent to be a compound of formula III, c) and the compound of formula III is reacted in 1,2-dehydro-6-nitrobenzene to the compound of formula IV in the presence of and d) hydrogenating the compound of formula IV in the presence of a metal catalyst. |