http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102190735-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42d90e70c0d612b8587fbe897976d33a |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate | 2011-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de56cf82a666e9defc172b19cca58230 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36dcb296eaaa982db93baac681307e61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1455f8350c545d4f82d35eb0aae0b8a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22c8cbc42f645149647387a51c8ec28f |
| publicationDate | 2014-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102190735-B |
| titleOfInvention | Fusion protein TAT (transactivator of transcription)-OCT4 (octamer-binding transcription factor 4), and coding gene and application thereof |
| abstract | The invention discloses a fusion protein TAT (transactivator of transcription)-OCT4 (octamer-binding transcription factor 4), and a coding gene and application thereof. The fusion protein provided by the invention comprises a TAT transmembrane peptide and a cell reprogramming correlation factor combined with an amino end or carboxyl end of the TAT transmembrane peptide. After the fusion protein-TAT OCT4 is used for treating HAFs (human aortic fibroblasts), the proliferation of the fibroblasts is promoted, and the enhancement of the expression level of the cyclins in the fibroblasts is promoted. The TAT transmembrane peptide transported nuclei transcription factor protein can be used as a cell reprogramming method, and can have important application prospects in cell induction and clinic. |
| priorityDate | 2010-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.