abstract |
The invention relates to a method for preparing an N-substituted pyrrole derivative. The method comprises the step of carrying out a reaction on aromatic aldehyde and 4-hydroxy-L-proline in a reaction medium at the temperature of 80 DEG C-200 DEG C in the presence of an acidic catalyst so as to prepare a target product. The method for preparing the N-substituted pyrrole derivative has the advantages that a raw material is cheap and available, operation is simple and practicable, inert gas dose not need to be used for protection in the whole preparation process, yield is high, and the like. |