| abstract |
The invention relates to a chiral hydrogenised H8-BINOL dual-phosphine compound the structure of which is shown in the following formula (I), wherein R1 and R2 are halogens, H or C1-C10 fatty groups; R3 is H or C1-C10 fatty groups; R4 is halogen, amino, nitro, H, C1-C10 fatty group or C1-C10 aromatic group; and X is phenyl, substituted phenyl, cyclohexyl, substituted cyclohexyl, a C6-C30 aromatic group, a C6-C30 heteocyclic aromatic group containing one or more of N, S and O. The invention also provides a catalyst which contains the compound and is used for an asymmetric catalytic hydrogenation reaction. By using the catalyst in the imine asymmetric hydrogenation reaction, above 90% of antipodes and more than above 100000 of conversion numbers can be achieved. |