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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b95f751471efaba7045444097410bb5a
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publicationDate 2013-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102126934-B
titleOfInvention Paraterphenyl derivative and application thereof in preparation of antitumor medicaments
abstract The invention discloses a paraterphenyl derivative. The paraterphenyl derivative has a compound structural formula shown as a formula (I) in the specification, wherein R1 is hydroxyl or methoxyl; R2 is hydrogen, hydroxyl or methoxyl; R3 is hydrogen, hydroxyl or methoxyl; R4 is hydrogen, hydroxyl or methoxyl; R5 is hydroxyl or methoxyl; and R6 is hydroxyl or methoxyl. The paraterphenyl derivative is obtained by coupling Suzuki with demthylating boron tribromide. A test shows that the paraterphenyl derivative has higher cytotoxin activity and potential of being developed into antitumor medicaments.
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