http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102120733-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3fab15895eb59644225598b1c9b9aea |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-56 |
| filingDate | 2010-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6532ea3116c469f0954f8695ae4c1d48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_606e0f4405d0b91b661cb73f32c42214 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b8ad76026455cc322bf61696b3f50d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a46f061fe6ad25e128a11011b3362edc |
| publicationDate | 2013-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102120733-B |
| titleOfInvention | Preparation method of Febuxostat |
| abstract | The invention relates to a preparation method of Febuxostat. In the preparation method, 2,4-dihalogenated phenol (a compound 1) which is cheap and is easy to obtain is used as a starting material, and the Febuxostat is synthesized by means of a new route comprising the steps of alkylation, cyaniding, sulfo-formylation, cyclization, and deprotection. The preparation method provided by the invention has a short route, and low-toxicity cuprous cyanide is used for cyaniding and virulent compounds such as potassium cyanide, sodium cyanide and the like are avoided, so that the process safety is greatly improved. |
| priorityDate | 2010-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.