http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102115449-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_066af93d226b9a8b1151cb1bc45bd190 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c5f724547c58bf7b904dc0ce8a7566e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-22 |
| filingDate | 2009-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34ae91a98940c805b5143291a3d28e57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d89e41acefc237f5a4b877323483fc7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c1d08b9c5c5492f5671890486a7277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14cd5e209c7ee4c8a7a0d02efbc810ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_194c9db5cf204105958e374e77c244dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b5e7155b8fd272fdc27b93356a7798a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7c7a01a5f4c2f46c817e52fc0c0831a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9423f6efb6e5e2a91e3ab228c59bb98 |
| publicationDate | 2014-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102115449-B |
| titleOfInvention | Novel method for preparing pregabalin raceme hydrochloride |
| abstract | The invention discloses a route and method for preparing 3-aminomethyl-5-methylhexanoic acid, namely pregabalin raceme hydrochloride. The method comprises the following steps of: performing condensation on 4-methyl-2-pentanone to obtain a compound in a formula (1), and performing reduction to obtain a compound in a formula (2); performing halogenation or esterification to obtain a compound in a formula (3a), and performing substitution to obtain a compound in a formula (4), or performing elimination on the compound in the formula (3a) to obtain a compound in a formula (3b) and performing addition to obtain a compound in the formula (4); and performing reduction and acidolysis on the compound in the formula (4) to obtain a pregabalin hydrochloride compound in a formula (6). The method is easy to operate, mild in reaction conditions, and low in cost, and is suitable for large-scale industrial production. |
| priorityDate | 2009-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.