abstract |
The present invention provides a new compound of formula I with agitation effect on a delta subtype peroxisome proliferator-activated receptor (PPAR delta), a pharmaceutical composition containing such compound, and the preparation method and the use in the manufacture of a medicament for treating or preventing disease that can be treated or prevented by activating PPAR delta thereof, in which the said disease is selected from metabolic syndrome, obesity, lipid abnormality, pathoglycemia, insulin resistance, senile dementia and tumor. The invention also relates to a new intermediate used in the preparation of said new compound and the preparation method thereof. The formula I is shown in the description. |