| abstract |
The invention provides a method for synthesizing aromatic amine. A reaction formula is shown in the specifications, wherein when X is nitrogen, a substituent group R can be 3-/5-nitro, 3-/5-cyan, 3-/5-trifluoromethyl or 3-/5-halo (fluorine, chlorine, bromine or iodine); when X is carbon, R can be 2-/4-nitro, 2-/4-cyan, 2-/4-trifluoromethyl or 2-nitro-4-chlorine; R1 and R2 refer to hydrogen, alkyl, alkyl alcohol, benzyl or-(CH2)n-(n=2-6) naphthenic base respectively; reaction alkali is caesium carbonate, potassium phosphate, pyridine, triethylamine, sodium bicarbonate, potassium carbonate, sodium/potassium hydroxide or sodium/potassium alkoxide; a reaction solvent is dioxane, toluol, dimethyl sulfoxide, dimethyl formamide, acetonitrile, tetrahydrofuran or acetone; and the reaction is implemented in the conventional heating state. In the method, raw materials are readily available, the process is simple, the reaction condition is mild, the application range is wide, and a plurality of aromatic amine compounds can be synthesized by different substrates. |