http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102091329-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5127fe8b5461c986356d7da71502405a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-23 |
| filingDate | 2011-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a757dccca92c7d7753895c4d297afac7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f81924434f3a4f99024f05fc5d29f48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7c36c90478f048daee3a7f1f2201006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6809afd7d8fde1dfa4b48c337cbcf994 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e212d6ea63edf445a6ed68c7077f780 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1acd926c9ca976e63c0bfd40ee3c809a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72086c8e25eef8d8940f0f9082566fcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc3a5fc0b9f69b90e3c69f7d43639d26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d488635bdc093a941d714a47187200af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_125925f016030ff385b6c841c8940f04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7137c05012373f2fd1b56098c25ef894 |
| publicationDate | 2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102091329-B |
| titleOfInvention | Preparation method of inactivated porcine parvovirus vaccine and product thereof |
| abstract | The invention discloses a preparation method of inactivated porcine parvovirus vaccine, comprising the following steps: (1) inoculating ST (swine testicle) cells with lentogen strains of porcine parvovirus, culturing to obtain production virus seeds; (2) adding treated microcarriers to a cell growth medium in a bioreactor, stirring; (3) inoculating the ST cells into the microcarriers in the bioreactor for cell reproduction and culturing; (4) infecting the suspension cultured ST cells in the bioreactor with the production virus seeds of the porcine parvovirus for virus reproduction and culturing; and (5) gathering the reproduced virus liquid, inactivating and preparing the vaccine. The method provided by the invention has long cell hold time, high cell viability and high density of living cells, and is favorable for continuous reproduction of virus, so that the prepared virus liquid has high virus titer. The production processes of the method disclosed by the invention are tightly and smoothly linked, the production scale is easy to enlarge, the porcine parvovirus is convenient to gather and stable in quality, and the method can obviously lower the production cost and effectively improve the yield and quality of the vaccine. |
| priorityDate | 2011-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.