http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102086179-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76860418b52f9c22202206cbdf960a27 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-247 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-784 |
filingDate | 2009-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b972921821faa8e649ab9c0fe3c89445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d2e579d54657f3cdc973418a40d309a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_474a1f72f972d6181898ab1d98bdc3dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc1c59f110f3de5c35f76aee63f50b8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2a96601a40d86805abb8bec0bf259c8 |
publicationDate | 2013-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102086179-B |
titleOfInvention | Synthesis method of biaryl compound |
abstract | The invention provides a reaction method which comprises the following step of: carrying out Suzuki-Miyaura coupling reaction on aryl or heteroarylboronic acid and aryl or heteroaryl iodide or bromide with a diaryl diamine compound as a ligand and metallic iron salt as a catalyst. The diaryl diamine ligand can be non-substituted, mono-substituted, disubstituted or multisubstituted 2,2'-diamidodiphenyl on nitrogen or aromatic rings. The catalyst and the ligand utilized by the invention have low price and are easily obtained and stable in air. In addition, by utilizing a catalysis system, the Suzuki-Miyaura coupling reaction of bromides including inactive bromides can be realized, which cannot be realized or is difficultly realized by utilizing the reaction catalyzed by other metallic iron salts in documents. Compared with the ligand reported in the documents, the ligand adopted by the invention has obviously low price and favourable industrial application prospect. |
priorityDate | 2009-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.