http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102086179-B

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Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76860418b52f9c22202206cbdf960a27
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-235
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-784
filingDate 2009-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b972921821faa8e649ab9c0fe3c89445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d2e579d54657f3cdc973418a40d309a
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publicationDate 2013-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102086179-B
titleOfInvention Synthesis method of biaryl compound
abstract The invention provides a reaction method which comprises the following step of: carrying out Suzuki-Miyaura coupling reaction on aryl or heteroarylboronic acid and aryl or heteroaryl iodide or bromide with a diaryl diamine compound as a ligand and metallic iron salt as a catalyst. The diaryl diamine ligand can be non-substituted, mono-substituted, disubstituted or multisubstituted 2,2'-diamidodiphenyl on nitrogen or aromatic rings. The catalyst and the ligand utilized by the invention have low price and are easily obtained and stable in air. In addition, by utilizing a catalysis system, the Suzuki-Miyaura coupling reaction of bromides including inactive bromides can be realized, which cannot be realized or is difficultly realized by utilizing the reaction catalyzed by other metallic iron salts in documents. Compared with the ligand reported in the documents, the ligand adopted by the invention has obviously low price and favourable industrial application prospect.
priorityDate 2009-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 28.