http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102076343-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5670a8f1f070df32157428d3a7ba55be |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-392 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
| filingDate | 2009-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_116164a1c53ee943f933a7fdd350ccb6 |
| publicationDate | 2011-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102076343-A |
| titleOfInvention | 6-substituted estradiol derivatives and methods of use |
| abstract | Wherein R1 and Z are as described above, X is selected from the group consisting of C1 -C6 alkyl, a substituted alkyl, a halogen, a halogenated alkyl, a glucoronide, -NH2, -SO2NH2, COOH, -CN, -CH2CN, -NHCN, -CHO, -COOsalt, -0S02alkyl, -SH, SCH3 -CH (CH2) nCOOCH3, - (CH2) n-O-CH3, -CH2OH, - (CH2) n-O-NH2, NH (CH2) nCH3, NH (CH2) nOCH3, - NH (CH2) nCHOH- COOH, - N (CH3) 2, 10 (CH2)n(NH)CH20H, -NHCOOH, -(CH2)nNHCOOH, -N02, -SCN, -SO2alkyl, -B (OH) 2, - (CH2) nN (CH3) -S02 NH3, - (CH2) nNH-S02-NH2, -NHC (=S) CH3, and -NHNH2, R3 is selected from the group consisting of H, a C1-C6 alkyl, a substituted alkyl, a halogen, and ahalogenated alkyl, R4 and Y are independently selected from a group consisting of O, -OH, -H, a -C1-C6 alkyl, a substituted alkyl, a halogen, a halogenated alkyl, a sulfate, a glucoronide, a bulky group, a phenyl or a substituted phenyl group, a cyclo- or heterocyclo group, pipepdine, piperazine, morpholine, pypmidine, -NH2, 20 N(CH2)n CH3 etc, and the respective epantiomers, other stereochemical isomers, hydrates, solvates, tautomers and pharmaceutically acceptable salts of said compounds. |
| priorityDate | 2008-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID467409924 |
Total number of triples: 21.