http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102072931-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49790ed5b8ddc5fa27a1d47732c612df |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C04B41-53 |
| filingDate | 2010-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa4ebc6d87d7777a96833c426faa91c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8d267600e9b8fb29a0aeeeb53eb66cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_107ee49c8daeecc34c377c5ecd4e0ee4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c0bddc5ca7679dd855174ae7a2cab83 |
| publicationDate | 2013-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102072931-B |
| titleOfInvention | Method for preparing biosensor based on silicon nanowires and application of biosensor in detecting DNA |
| abstract | The invention discloses a method for preparing a biosensor based on silicon nanowires and application of the biosensor to detecting DNA. The method is characterized by preparing the silicon nanowires by a wet chemical method, modifying gold nanoparticles on the silicon nanowires via a silane coupling agent and grafting a probe DNA on the silicon nanowires through binding of chemical bonds between the gold nanoparticles and the DNA to prepare a sensor probe. The sensor is applied to detecting the unknown DNA sequences in the target solution to be detected. The detecting results are mainly obtained by analyzing the data measured by cyclic voltammetry. The invention has the following advantages: (1) mass production can be carried out through simple microprocessing technology, the cost is low and the microprocessing technic is compatible with the large scale integration technology; (2) the biosensor mainly utilizes the specificity and biocompatibility among the silicon nanowires, the gold nanoparticles and the DNA, is easy to realize and has wide applicability; and (3) the biosensor is simple and convenient to manufacture, has good repeatability and high sensibility, is easy to realize microminiaturization and can realize real-time monitoring. |
| priorityDate | 2010-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.