| abstract |
The invention relates to a preparation method for a 4-substituted phenylamino-7-substituted alkoxy-quinazoline derivant (chemical formula I), which comprises the step of: carrying out etherifying reaction on compounds shown in a general formula II and a general formula III, wherein R1, R2, R3, m, n, p and q respectively have meanings defined in the specification. The compounds have valuable pharmacological properties, and in particular, have inhibiting effect on signal transmission caused by protein tyrosine kinase (PTK). The method provided in the invention has the advantages of simpleness in operation, high yield and low cost and is suitable for industrial production. |