http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102070523-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfa3ea80cad3819ce2b58bf1b5dbc7f7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-50 |
| filingDate | 2010-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7229778c9290b8f00696e0e162c35d97 |
| publicationDate | 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102070523-B |
| titleOfInvention | Novel method for preparing 3-hydroxylquinaldine-4-carboxylic acid |
| abstract | The invention relates to a novel method for preparing 3-hydroxylquinaldine-4-carboxylic acid. The 3-hydroxylquinaldine-4-carboxylic acid produced by the prior art has low purity. To solve the problem, the novel method for preparing the 3-hydroxylquinaldine-4-carboxylic acid comprises the following steps of: (1) adding 1.0 molar part of solid isatin into enough clear water, then adding 1.0 equivalent molar part of inorganic base, mixing and dissolving, filtering, and collecting filtrate; and (2) adding 1.0 equivalent molar part of inorganic base into the obtained filtrate, dropwise adding 1 to 2.0 molar parts of monochloroacetone, then dropwise adding hydrochloric acid to adjust the pH value to be 7, then emptying and filtering, collecting a filter cake, and drying to obtain a finished product. BY the method, the content and purity of the 3-hydroxylquinaldine-4-carboxylic acid are improved on the premise of not increasing equipment, raw materials, processes and the like; and the purity of the 3-hydroxylquinaldine-4-carboxylic acid prepared by the method is over 97 percent, and the yield is more than or equal to 95 percent. |
| priorityDate | 2010-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.