http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102070433-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e67650c6feaae259cffe0c2c97b3a8c9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C53-126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-32 |
| filingDate | 2010-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fe8a53108574daa03a58f1c049b3a31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02a05397cdf9cf962cb2ae2d02ecbd0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ac6c5284a4e40260dee65547c3daed7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e868f15dd0f29be9d010473f8ec5b022 |
| publicationDate | 2013-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102070433-B |
| titleOfInvention | Preparation method for aryl acetic acid derivative |
| abstract | The invention discloses a preparation method for an aryl acetic acid derivative. The preparation method comprises the following specific steps of: (1) adding sodium acetate, acetic anhydride and a cyclization agent into aryl methanal or alkyl original aliphatic aldehyde having more than four carbon atoms, and performing cyclization reaction to obtain an aryl oxazolone derivative, wherein the cyclization agent is N-acyl-glycine or an analogue thereof; and (2) uniformly mixing the aryl oxazolone derivative and aqueous alkali, adding an oxidizing agent and performing oxidization reaction to obtain the corresponding aryl acetic acid derivative, wherein the alkali is sodium hydroxide solution or potassium hydroxide, and the oxidizing agent is peroxy acid. Compared with the prior art, the method is mild in reaction condition, short in reaction steps, short in preparation cycle, low in cost, simple in posttreatment and low in environmental pollution, and is applicable for preparation of the aryl acetic acid derivative; by the method, the raw materials are readily available; moreover, the product prepared by the method is high in purity and stable in quality, and the method is suitable for large-scale industrial production. |
| priorityDate | 2010-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.