| abstract |
The present invention relates to 1-aryl-3-aniline-5-alkyl-1,2,4-triazole derivatives of formula (I) and analogues or pharmaceutically acceptable salts thereof, methods for preparing them, containing them pharmaceutical composition and its use in therapy. In particular, the present invention relates to potent positive allosteric modulators of nicotinic acetylcholine receptors, which positive allosteric modulators have the ability to increase the potency of nicotinic receptor agonists. |