http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102060840-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0112b3c4165b3c7db770fae1ebe5c0b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 |
| filingDate | 2010-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5265c0677cbd0650257e7fce4ffb7f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d58e6f837b2c96dc0837f22476b9500 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ff3b3d5875b25faefd5e5b883165d9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e59ffa730738e06c12a5f50e7f9e6171 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0909b011490aed44c3c7f7d6eafe630b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40d17adde043ce28d23257489dc80589 |
| publicationDate | 2013-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102060840-B |
| titleOfInvention | Preparation method of articaine hydrochloride |
| abstract | The invention discloses a preparation method of articaine hydrochloride. The method comprises the following steps: carrying out amidation reaction on 4-methyl-3-aminothiophene-2-methyl formate utilized as a raw material and 2-chloro propionyl chloride; then carrying out the ammoniation reaction with propylamine; and carrying out salification reaction with concentrated hydrochloric acid, thus obtaining the articaine hydrochloride. The invention has the following advantages: the process route of the preparation method is suitable for industrial production, the rigorous reaction conditions are avoided, raw materials are easy to obtain, the operation is simple, and the yield coefficient is high. |
| priorityDate | 2010-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.