| abstract |
The invention discloses a preparation method for a prostaglandin intermediate. The method comprises the step of: (1) mixing a compound represented by a formula II and a substitutive o-iodobenzoic acid type compound represented by a formula III to obtain a compound represented by a formula I, wherein R1 is C1-C4 straight chain or alkyl, phenyl or substitutive phenyl which contains branch chains; R2 is tetrahydropregnenolone (THP), silane radical substituted by trialkyl, alkyl acyl, benzoyl or benzoyl of which the benzene ring is provided with a substituent; and R3 is acetoxy. |