| abstract |
The invention relates to a group of 3,7,10-trimethyl-silatrane Schiff base derivatives, and preparation and application thereof. The preparation method comprises the following steps of: reacting triisopropanolamine with gamma-aminopropyltriethoxysilane to obtain a gamma-amino propyl-3,7,10-trimethyl silatrane intermediate; and then performing a nucleophilic addition reaction of the gamma-amino propyl-3,7,10-trimethyl silatrane intermediate and different substituent-containing aldehyde in benzene solvent to obtain the 3,7,10-trimethyl-silatrane Schiff base derivatives. The 3,7,10-trimethyl-silatrane Schiff base derivatives have high plant growth regulating activity and high anti-inflammatory activity and can be applied to the preparation of a plant growth regulating agent and a cyclooxygenase (COX) inhibitor. The formula is shown as (I) in the specification. |