http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102002476-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97651de1ceeb2411cad2574055776c20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
| filingDate | 2010-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0da669d7ae1e01f10de4615eb02ef5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f7de20f85f484c832c5d0302f63e1c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfa4748651655606f991fbbe84162146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a83eca9b2778a985578abdb6eec3921 |
| publicationDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102002476-B |
| titleOfInvention | Human mucous membrane living tissue model cultured in vitro as well as building method and application thereof |
| abstract | The invention relates to an in vitro infection model of infection diseases, in particular to an infection model used in sexual transmitted disease prevention and mucous membrane immunization and a building method thereof, more specifically relates to a human mucous membrane living tissue model cultured in vitro as well as a building method and application thereof, which belong to the technical field of biomedicine. The human mucous membrane living tissue model cultured in vitro is provided by preprocessing an in vitro tissue sample, adopting different tissue culture modes, observing the form variation of the tissue cultured for different days, detecting tissue viability, evaluating the sensitivity of the tissue to medicine concentration variation and adopting a pseudovirus infection mucous membrane tissue. The model is suitable for the in vitro infection of in vitro human living tissues, and is cultured in vitro for a long term to discover strong viability. The model reproduces the real trajectory of HIV (Human immunodeficiency virus)-1 infecting human target cells, and provides a technical platform for the research on HIV-1 mucous membrane infection mechanism and the evaluation research on the safety and effectiveness of a novel biologic prevention technology before clinic application. The method can be developed in biosafety secondary laboratories. |
| priorityDate | 2010-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.