http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101993442-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7796fb76ebba3401d8a0c79b078a6985 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-00 |
| filingDate | 2009-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76995cc91a6446f7830dc4a812fbe802 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e8b0e25625eeb96717ceb33b067ee58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d0ac2a6dec2df4781628b6ab89545f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ba5dcb8254e5d12900d72b14bf06e2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90e59a33f52d85e7aa44f814edfe4544 |
| publicationDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101993442-B |
| titleOfInvention | Novel crystal forms of benzilic acid nortropinyl hydrochloride and preparation method thereof |
| abstract | The invention discloses novel crystal forms of benzilic acid nortropinyl hydrochloride which is the core intermediate of trospium chloride. The novel crystal forms disclosed in the invention comprise a crystal form A, a crystal form B and a crystal form C, wherein the crystal form A has characteristic peaks at the positions of 5.52, 10.88, 17.28, 21.88 and 33.14 of an X-ray powder diffraction spectrum represented by the angle of 2 theta; the crystal form B has the characteristic peaks at the positions of 6.02, 8.74, 12.34, 15.38, 16.62, 17.54, 18.80, 19.36, 20.66, 21.78, 22.48, 22.92 and 24.90 of the X-ray powder diffraction spectrum represented by the angle of 2 theta; and the crystal form C has the characteristic peaks at the positions of 5.42, 11.32, 16.80, 17.16, 18.50, 19.92, 21.88 and 24.22 of the X-ray powder diffraction spectrum represented by the angle of 2 theta. The melting point of the crystal form A is 234.0-235.0 DEG C, the melting point of the crystal form B is 224.0-227.0 DEG C and the melting point of the crystal form C is 222.0-223.0 DEG C. The invention also discloses applications of the crystal forms A, B and C of the benzilic acid nortropinyl hydrochloride in preparing trospium chloride drugs for curing uroclepsia drugs. |
| priorityDate | 2009-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.