http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101993382-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-43 |
| filingDate | 2009-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101993382-B |
| titleOfInvention | Aromatic amine derivative or analog and application thereof |
| abstract | The invention belongs to the field of medicinal chemistry, relates to an aromatic amine derivative or an analog and an application thereof, in particular to the aromatic amine derivative for treating diseases associated with abnormal increase in the level of sphingomyelin, and the analog and a preparation method thereof, a salt of the compound, as well as medicament taking the compound or the salt as an active ingredient. The aromatic amine derivative or the analog thereof has a structure of formula I, II or III. The aromatic amine derivative and the analog thereof of the invention as a sphingomyelin synthase inhibitor have activity of inhibiting micro-molar sphingomyelin synthase, can be used as a small-molecule inhibitor of the sphingomyelin synthase to inhibit the activity of synthesized sphingomyelin, can be further prepared into the medicament for treating diseases caused by increasing the level of the sphingomyelin of the targeted sphingomyelin synthase, such as atherosclerosis. |
| priorityDate | 2009-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 153.