http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101985424-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d40285e27f4ed83b8728b0d477404958 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-45 |
| filingDate | 2010-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda75673f32c7d2ec73b131f0978afd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fac74cbc0e6c2ccca73ca42896090009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12689715a76e29376835543d042632ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f521cf9342b023482f0b3a236a80d20a |
| publicationDate | 2013-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101985424-B |
| titleOfInvention | Method for synthesizing o-nitroacetophenone compound |
| abstract | The invention provides a method for synthesizing o-nitroacetophenone compound, relating to a method for synthesizing organic compound. The invention takes acetophenone (can contain various substituent groups) as raw material directly, carbonyl group is converted into hydroxyimino, then palladium is taken as catalyst, carbon-hydrogen bond activation single nitration on the adjacent position of hydroxyimino is realized in the presence of oxidant and nitration agent, and finally hydroxyimino is hydrolyzed into corresponding ketone again under the action of acid, thus realizing nitration of adjacent position of carbonyl group of acetophenone and obtaining a series of o-nitroacetophenone compounds. The invention is safe and environmentally friendly, no waste gas or waste water is produced; adaptability of substrate is good, adjacent position nitration on various substituent groups can be realized; regioselectivity of nitration reaction is good; various nitroacetophenones are directly taken as raw materials, and reaction process is simple, thus being a new approach for synthesizing o-nitroacetophenone compound containing substituent groups. |
| priorityDate | 2010-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.