http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101975829-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d20b2cdd2bb568e7aa17cb297993f2b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-739 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-8964 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-8969 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-8984 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-8945 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf0d1b884a2da860f7a8a3b5ded22baa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca86bee8f9d2df1d51b434f5266204a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a4518440cbcf398bf34d86a465a77c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0799e0ded3b802b23eb87ce3a5b03b0f |
| publicationDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101975829-B |
| titleOfInvention | Screening method and application of alpha-glucosidase inhibitor |
| abstract | The invention belongs to the field of traditional Chinese medicines. The screening method of an alpha-glucosidase inhibitor comprises the following steps of: (1) establishing in vitro screening models; establishing in vitro screening models of alpha-glucosidase and a substrate PNPG (Para Nitrobenzene-Beta-D-Galactose Pyranoside); (2) establishing a component library: selecting traditional Chinese medicines, systematically extracting each traditional Chinese medicine with various (more than two kinds) solvents according to a similar compatible principle according to the polarities from low to high, wherein multiple extracting parts can be obtained for each traditional Chinese medicine by adopting the method; and (3) screening: blending all the extracting parts of the traditional Chinese medicines into a solution with a certain concentration, adding the solution to a reaction model, and calculating the inhibition rate. The screening method is simple, reasonable and easy to operate and can be used for finally screening out traditional Chinese medicines and traditional Chinese medicine components having obvious inhibition effects on the alpha-glucosidase. In addition, the screened traditional Chinese medicines and the traditional Chinese medicine components can be used for developing products aiming to inhibit the alpha-glucosidase and particularly used for developing drugs for reducing the blood sugar and has industrialization significance. |
| priorityDate | 2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.