| abstract |
The invention belongs to the field of medical compound synthesis, and in particular relates to deuterated crizotinib as well as a preparation method and application thereof. The structural formulas of the deuterated crizotinib and a derivant thereof are showed as (I) or (II). The crizotinib deuterated derivant provided by the invention has the same medical effect as crizotinib, thereby providing a new compound for synthesizing a new antineoplastic agent and a new way for the synthesis of the antineoplastic agent. |