| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_129e393582e6bdf4029baf2206522f45 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1688 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-04 |
| filingDate |
2008-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a3624f95cf5d2e35579a4bbd7ab3d81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dafed71a429a7a4921dfbd9dd6b5de6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3b0f3fbde7030a58595fb4f57628308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7e79870e0a3e2d0cc1f8c46a47dcdf0 |
| publicationDate |
2012-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-101965187-B |
| titleOfInvention |
Crystalline micropowder particles |
| abstract |
Crystalline particles of N-(17-cyclopropylmethyl-4,5a-epoxy-3,14-dihydroxy-morphinan-6ss-yl)-phthalimide or a pharmaceutically acceptable salt thereof. Theses crystalline particles have a particle diameter distribution, wherein the particle diameter (D50) at the point attaining a cumulative frequency of 50% in volume distribution counted from the smallest particle diameter ranges from 1 to 30 [mu]m while the particle diameter (D90) at the point attaining a cumulative frequency of 90% in volume distribution counted from the smallest particle diameter is not more than 90 [mu]m, and a degree of crystallization of 80% or more. These crystalline particles make it possible to improve the biological availability of the active ingredient while ensuring the storage stability of the above-described compound. |
| priorityDate |
2007-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |