| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64fab711e94aa910dfb7511bb1bf834e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-58 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-04 |
| filingDate |
2009-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b893764d0542c7e29fcf2fa023f2c34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1e155d192dac1cad21e92098762dbf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_128cd4d122a6e96c4e5a04965d8f27e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ae89276e7376ed9e3bec7bf1b8b6c6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_411343f549ce574170d98c9b9d0ad210
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fde2a138aa7d3fd8b12bcf4d8552a03 |
| publicationDate |
2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-101952270-B |
| titleOfInvention |
Process for preparing nebivolol |
| abstract |
The present invention relates to a process for reducing a compound of formula (I) wherein X is halogen, a hydroxy group, an alkylsulfoniloxy group or an arylsulfonyloxy group; to give a compound of formula (II) as a diastereoisomerically pure compound of RS/SR configuration characterized in that said reduction is carried out by the use of (+)-B- chlorodiisopinocampheylborane or (-)-B- chlorodiisopinocampheylborane. The compounds of formula (II) are useful as intermediates for the preparation of Nebivolol. |
| priorityDate |
2008-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |