http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101947205-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_103ebd6dea1e0f4e9bc4f2dcb992d776 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 |
filingDate | 2010-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dbd8a8b6e16e77ff28aa578f6582712 |
publicationDate | 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101947205-B |
titleOfInvention | Novel galanthamine sustained-release preparation and preparation method thereof |
abstract | The invention relates to a novel galanthamine sustained-release preparation and a preparation method thereof. The invention is characterized in that: one or mixture of more of microcrystalline cellulose, starch and derivatives thereof, lactin, hydroxypropyl methyl cellulose and ethocel is taken as a sustained-release substrate; the preparation method mainly comprises the following steps of: preparing galanthamine, a filler, a lubricating agent and an adhesive into medicament-containing pellets through an extruding and rounding method; and respectively coating an isolation layer and a sustained-release layer on a fluidized bed to prepare the novel galanthamine sustained-release preparation; and a membrane controlled- release technique and a skeleton technique are combined to be applied to the control of the medicament release rate. The preparation process is simple and feasible; and the prepared galanthamine sustained-release preparation solves the problem that patients suffering from Alzheimer disease have low independent consciousness and cannot take the medicine for multiple times each day, and improves the medication compliance of the patients. |
priorityDate | 2010-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.