http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101947205-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_103ebd6dea1e0f4e9bc4f2dcb992d776
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38
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filingDate 2010-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dbd8a8b6e16e77ff28aa578f6582712
publicationDate 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101947205-B
titleOfInvention Novel galanthamine sustained-release preparation and preparation method thereof
abstract The invention relates to a novel galanthamine sustained-release preparation and a preparation method thereof. The invention is characterized in that: one or mixture of more of microcrystalline cellulose, starch and derivatives thereof, lactin, hydroxypropyl methyl cellulose and ethocel is taken as a sustained-release substrate; the preparation method mainly comprises the following steps of: preparing galanthamine, a filler, a lubricating agent and an adhesive into medicament-containing pellets through an extruding and rounding method; and respectively coating an isolation layer and a sustained-release layer on a fluidized bed to prepare the novel galanthamine sustained-release preparation; and a membrane controlled- release technique and a skeleton technique are combined to be applied to the control of the medicament release rate. The preparation process is simple and feasible; and the prepared galanthamine sustained-release preparation solves the problem that patients suffering from Alzheimer disease have low independent consciousness and cannot take the medicine for multiple times each day, and improves the medication compliance of the patients.
priorityDate 2010-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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