http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101921268-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2010-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101921268-B |
titleOfInvention | 5-thiazole amide compound and biological applications |
abstract | The present invention relates to a kind of 5 thiazole amide compounds and biological applications, its structural formula is The invention provides 5 thiazole amide compounds of targeting AKT/PKB kinases (ATP-binding site) represented by logical formula (I).Experiment proves, thiazole amide AKT inhibitor involved in the present invention can significantly inhibit the kinase whose activity of AKT in vitro, and the multiple AKT high tumor cell line of activity is had the strongest inhibited proliferation, show that thiazole amide compound can be used for preparing antitumor drug. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018137555-A1 |
priorityDate | 2010-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 206.