| abstract |
The present invention relates to pyrimidine compounds represented by the following formula [I] and pharmaceutically acceptable salts thereof Wherein each symbol is as defined in the instructions, the medicines containing these compounds for the prevention or treatment of diseases caused by unwanted cell proliferation, especially antineoplastic medicines. The compounds of the present invention have strong unwanted cell proliferation inhibitory effects, especially antitumor effects, and are used as antitumor drugs, antirheumatic drugs, etc. for the prevention and treatment of cancer. In addition, it can be a more effective antitumor drug by using it in combination with other antitumor drugs such as alkylating agents, metabolic antagonists, and the like. |