| abstract |
The invention relates to a rhoifolin and a prepared medicament application thereof. The method for extracting the rhoifolin comprises the following steps of: taking turpinia formosana leaves or exocarpium citrl grandis, adding 5-15 times of 30-90 percent ethanol for carrying out refluxing extraction for 1-3 times and filtering, wherein each refluxing extraction is carried out for 1-3 hours; combining filter liquid and recycling ethanol; eluting an aqueous solution by a macroporous resin column, collecting an eluted part, depressurizing for concentrating and drying to obtain the mixed total glycoside of the rhoifolin; and separating, combining rhoifolin fractions and crystallizing to obtain pure rhoifolin. The rhoifolin can be used as a neuraminidase inhibitor for preventing and treating influenza and made into a pharmaceutically acceptable formulation. |