http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101905030-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0e50b78de0c148191267061842b3085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f68ddaa0ddd894016af217422d657c22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L75-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-12 |
filingDate | 2010-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aecc9339c9a5caebc8af877a2a34bfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daaf2055107a1b0a609ea3b33d418d93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72cebbfba04ec2feb6de4cb70eb25c9b |
publicationDate | 2013-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101905030-B |
titleOfInvention | Method for preparing fibroin-modified polyurethane biomedical material |
abstract | The invention discloses a method for preparing a fibroin-modified polyurethane biomedical material. A polyurethane material is taken as a substrate layer, and the method comprises the following steps of: performing covalent grafting on double bond-containing unsaturated carboxylic acid on the surface of the polyurethane material in the presence of an oxidizing agent to form polycarboxylic acid; and reacting the carboxyl on the surface layer of the material to form amide ester in the presence of carbodiimide (EDC), and reacting the amide ester with an amino group on a fibroin macromolecule chain so as to generate an amido bond to form a fibroin-grafted polyurethane film with a layered structure. The molded material has good compatibility with biological tissues, also has excellent mechanical property and stable composite interface, and is an ideal biomaterial. |
priorityDate | 2010-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.