http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101880405-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L3-12 |
| filingDate | 2010-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70b1af4034717eef09bfbc60aac8fdc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1ebadccb828d5ae7f73d2853f747645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5426e4bc4c493295d17872f5adb90948 |
| publicationDate | 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101880405-B |
| titleOfInvention | Method for preparing biodegradable spherical porous starch foam and application |
| abstract | The invention relates to a process for preparing biodegradable spherical porous starch foam and a biodegradable spherical porous starch foam administration system for an insoluble medicament. The process adopts an emulsifying-freeze thawing combined solvent displacement method, and comprises the following steps of: performing high-speed stirring or homogenizing treatment (emulsion homogenizing machine) on starch-melted aqueous solution with certain concentration serving as a water phase, methylbenzene/chloroform mixed solution (or other emulsion oil phase) serving as an oil phase and Span80 (or other W/O emulsifying agent) serving as an emulsifying agent to form uniform W/O emulsion, standing the emulsion for certain time at the temperature of 20 DEG C below zero, demixing the emulsion by gelling, dehydrating the layers in turn by adopting balance of aqueous solution of methanol with different concentrations, separating and removing the methylbenzene/chloroform layer by adopting a separating funnel, balancing the solution by using anhydrous ethanol, filtering the solution, and drying the filtrate with vacuum to obtain the biodegradable spherical porous starch foam. The foam material suitable to be used as an insoluble medicament carrier increases the specific surface area and water solubility of the insoluble medicament, and finally improves the bioavailability of the insoluble medicament. |
| priorityDate | 2010-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.