http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101874798-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e74277852f1aae0a3ff13f59a65456d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
| filingDate | 2010-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c668b1c9ea7d09cb184ee46d80e18f58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4168d075f43bfe5d199c09aaf74482c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_403454d199643a41762e82c894c42c56 |
| publicationDate | 2012-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101874798-B |
| titleOfInvention | Difunctional inhibitor of leukotriene A4 hydrolase and cyclooxygenase and application thereof |
| abstract | The invention relates to a difunctional inhibitor of leukotriene A4 hydrolase and cyclooxygenase, which is shown as the formula (I), a pharmaceutical compound containing the inhibitor as well as the application thereof in preparing medicaments for treating and preventing state of illness of a subject, which is induced by leukotriene A4 hydrolase and cyclooxygenase, the application in preparing medicaments for treating, preventing or inhibiting inflammation of the subject, and the application in preparing medicaments for inhibiting the activities of leukotriene A4 hydrolase and cyclooxygenase. In the formula, Ar represents 2-pyridyl, 4-pyridyl, 6-nitro-2-pyridyl, 2-pyrazinyl and relevant hexa-nitrogen heterocyclic ring, phenyl or represents a group in the formula (II), wherein P and Q in the group (II) are respectively at the two positions of 2, 3 and 4 or the benzene ring, and are same or different, and the P and Q respectively represent hydrogen, halogen, amido, nitro, trifluoromethyl, mesyl, mono-methanesulfonamide group, bi-methanesulfonamide group or methyl-sulfamide group. |
| priorityDate | 2010-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.