http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101831288-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6fbb91e3f8cdf858527814216aa11142
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B57-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06
filingDate 2010-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e6712355c9227996212a86a5f6b7859
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc94ac60ab27808dfbee47f1073e2f9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f90efbd975d39401845c544af6de476f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cef52ce133b0a88d559080a1696f5933
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3fcc7443774ed05d1767afd43fc825
publicationDate 2013-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101831288-B
titleOfInvention Amide derivative of rhodamine B and preparation method thereof
abstract The invention provides an amide derivative of rhodamine B and a preparation method thereof. In the method, rhodamine B dye with carboxyl on 1-site is used as a matrix and reacts with amine to generate the rhodamine B amide derivative. The method comprises the following steps of: dissolving the rhodamine B with carboxyl on the 1-site into a dry organic solvent, adding alkyl amine into the organic solvent, reacting the mixture under the protection of inert gas, and removing the solvent by reduced pressure distillation; and purifying the obtained substrate by using eluent through a chromatographic column, acidifying the purified substrate, drying the acidified product under vacuum, and removing the solvent to obtain a target product of the rhodamine B amide derivative. The amide derivative of the rhodamine B provided by the invention has the following structure.
priorityDate 2010-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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