http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101824068-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J53-00 |
filingDate | 2010-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56ba57e25867b434c52f6182412b0743 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3792549837e86cc12621b8864c95caf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81d727375b6ab086ac85e1e83367205e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71fcedabaa74b5e8a45b94c32d72d8ed |
publicationDate | 2015-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101824068-B |
titleOfInvention | Cyclic-ahltin type triterpenoid saponin compound and preparation method and application thereof |
abstract | The invention belongs to the technical field of medicines and provides a cyclic-ahltin type triterpenoid saponin compound and a preparation method and application thereof. The cyclic-ahltin type triterpenoid saponin compound is prepared by the steps of: obtaining an extracting solution or extract liquor by using a flash extraction technology or a solvent extraction method; processing the extracting solution or the extract liquor by using a non-polar resin column to obtain crude saponin; quickly processing the crude saponin by using a silica gel flash column chromatography, and then carrying out solvent gradient elution, and further separating and purifying by using a medium-low pressure column chromatography or open ODS (Oxide Dispersion Strengthened) column chromatography and an HPLC (High Performance Liquid Chromatography) technology. An LC-MS technology is used for detecting the components of the cyclic-ahltin type triterpenoid saponin compound in the preparation process. The prepared cyclic-ahltin type triterpenoid saponin compound has better anti-tumor activity. |
priorityDate | 2010-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.